Source monitoring

PubMed literature watch.

Daily monitoring of NCBI PubMed for new clinical-trial publications, results papers, safety analyses, meta-analyses, and reviews, scoped to your drugs, drug classes, sponsors, and indications.

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What PubMed is

PubMed is the U.S. National Library of Medicine's free citation database covering biomedical literature from MEDLINE, life-science journals, and online books. Access is via NCBI E-utilities, a free API that supports structured search across publication type, journal, MeSH headings, authors, affiliations, and publication date.

What Clinical Trial Signal monitors

Clinical-trial publications

New papers tagged as clinical trials, with phase, sponsor, and condition extracted where available.

Results papers

Results publications cross-referenced to registry NCT IDs where the link is in the record.

Safety analyses

Pharmacovigilance studies, FAERS analyses, and label-change-relevant literature.

Reviews and meta-analyses

Systematic reviews and meta-analyses that materially change the public evidence base.

Author and affiliation watches

KOL author watches for named investigators and institutions.

Europe PMC cross-reference

Preprint cross-reference via Europe PMC for early signal.

Why it matters

Trial results, safety analyses, and meta-analyses shift the public evidence base. New systematic reviews can move guideline conversations; new safety analyses can precede label discussion. Manual PubMed searching does not scale to a portfolio of drugs and competing programs; a structured watch does.

Who uses PubMed literature watch

Researchers

Topic and KOL watch

Stay current on a portfolio of drugs and investigators.

Consultants

Source-backed evidence briefs

Cite primary papers, not press summaries.

Analysts

Read-out paper detection

Pair PubMed results papers with registry events.

Journalists

Newly published evidence

Surface high-impact papers with author and affiliation context.

Source caveats

PubMed indexing lags peer-reviewed publication, and not every clinical paper is indexed as a "Clinical Trial" publication type. Preprint cross-reference via Europe PMC is provided where available, but preprints are not peer-reviewed. Clinical Trial Signal links to primary records and does not paraphrase study conclusions beyond the original abstract.

Start tracking literature

PubMed watchlists are included on Pro and above. Analyst Desk adds wire-feed cross-reference. Research Team adds disease-area dashboards.

See pricing See sample watchlists

Compliance-safe positioning. Clinical Trial Signal provides public-data research intelligence. It is not medical advice, legal advice, regulatory advice, investment advice, or a pharmacovigilance system of record. Literature signals are intended for research screening and should be reviewed by qualified professionals.